COMPLICATION

·         Gastrointestinal

·         GI hemorrhage

·         Malabsorption

·         Intestinal obstruction

·         Peritonitis

·         Appendicitis

·         Obstructive jaundice

·         Ileus

·         Pneumatosis intestinalis

·         Intestinal perforation

·         Intestinal infarction

·         Diarrhea

·         Pruritus

·         Ascites

·         Respiratory

·         Asthma or exacerbation of preexisting obstructive pulmonary disease

·         Pneumonitis

·         Respiratory failure⁸

·         Acute respiratory distress syndrome

·         Alveolar hemorrhage

·         Pleural effusion

·         Granulomatous lung disease

·          Pulmonary eosinophilia(Loeffler’s Syndrome)

·         Bronchospasm

·         Dermatologic

·         Larva currens

·         Purpura of the trunk and proximal extremities

·         Chronic urticaria

·         Neurologic

·         Meningitis due to enteric bacteria

·         Brain abscess

·         Vascular - Hyperinfection syndrome presenting as bacteremia (occasionally recurrent) due to enteric microorganisms (eg, E coli, Klebsiella pneumoniae, Enterococcus species including vancomycin-resistantEnterococcus faecium, Streptococcus bovis)

·         Renal -Nephrotic syndrome (rare)

·         Musculoskeletal -Reactive arthritis (rare)

·         Death

·         Anemia